Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91319
MIM: 610305
HGNC: 14236
Ensembl: ENSG00000099958
Variants:
dbSNP: 91319
ClinVar: 91319
TCGA: ENSG00000099958
COSMIC: DERL3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000099958 | ENST00000318109 | Q96Q80 |
| ENSG00000099958 | ENST00000404056 | E7EVA4 |
| ENSG00000099958 | ENST00000406855 | Q96Q80 |
| ENSG00000099958 | ENST00000476077 | Q96Q80 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36372158 | 2023 | Repression of DERL3 via DNA methylation by Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma. | 2 |
| 36372158 | 2023 | Repression of DERL3 via DNA methylation by Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma. | 2 |
| 31862624 | 2020 | DERL3 functions as a tumor suppressor in gastric cancer. | 6 |
| 32866644 | 2020 | Up-regulated DERL3 in fibroblast-like synoviocytes exacerbates inflammation of rheumatoid arthritis. | 1 |
| 31862624 | 2020 | DERL3 functions as a tumor suppressor in gastric cancer. | 6 |
| 32866644 | 2020 | Up-regulated DERL3 in fibroblast-like synoviocytes exacerbates inflammation of rheumatoid arthritis. | 1 |
| 28713959 | 2017 | Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells. | 12 |
| 28713959 | 2017 | Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells. | 12 |
| 24699711 | 2014 | A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect. | 60 |
| 24699711 | 2014 | A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect. | 60 |
| 16449189 | 2006 | Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. | 154 |
| 16449189 | 2006 | Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. | 154 |
Citation
Dessen P
DERL3 (derlin 3)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57571/derl3-(derlin-3)
