YEATS2 (YEATS domain containing 2)

2018-07-01  

Identity

HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
FAME4
FUSION GENES

Other Information

Locus ID:

NCBI: 55689
MIM: 613373
HGNC: 25489
Ensembl: ENSG00000163872

Variants:

dbSNP: 55689
ClinVar: 55689
TCGA: ENSG00000163872
COSMIC: YEATS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163872ENST00000305135Q9ULM3
ENSG00000163872ENST00000432781H0Y6M6

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386199712024Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.0
386199712024Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.0
346869482023YEATS2 regulates the activation of TAK1/NF-κB pathway and is critical for pancreatic ductal adenocarcinoma cell survival.4
346869482023YEATS2 regulates the activation of TAK1/NF-κB pathway and is critical for pancreatic ductal adenocarcinoma cell survival.4
327496782021YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration.16
345878742021YEATS domain-containing 2 (YEATS2), targeted by microRNA miR-378a-5p, regulates growth and metastasis in head and neck squamous cell carcinoma.2
327496782021YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration.16
345878742021YEATS domain-containing 2 (YEATS2), targeted by microRNA miR-378a-5p, regulates growth and metastasis in head and neck squamous cell carcinoma.2
315390322019TTTCA repeat insertions in an intron of YEATS2 in benign adult familial myoclonic epilepsy type 4.48
315390322019TTTCA repeat insertions in an intron of YEATS2 in benign adult familial myoclonic epilepsy type 4.48
290579182017YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.59
290579182017YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.59
271034312016YEATS2 is a selective histone crotonylation reader.91
271034312016YEATS2 is a selective histone crotonylation reader.91
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

YEATS2 (YEATS domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57572/yeats2-(yeats-domain-containing-2)