CIR1 (corepressor interacting with RBPJ, CIR1)

2018-07-01  

Identity

HGNC
CIR1
LOCATION
2q31.1
LOCUSID
9541
ALIAS
CIR
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9541
MIM: 605228
HGNC: 24217
Ensembl: ENSG00000138433

Variants:

dbSNP: 9541
ClinVar: 9541
TCGA: ENSG00000138433
COSMIC: CIR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138433ENST00000342016Q86X95
ENSG00000138433ENST00000377973H3BLY3

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Notch signaling pathwayKEGGko04330
Notch signaling pathwayKEGGhsa04330

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
275875432016Polymorphisms in cancer-related pathway genes and lung cancer.3
275875432016Polymorphisms in cancer-related pathway genes and lung cancer.3
156523502005CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.5
156523502005CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.5

Citation

Dessen P

CIR1 (corepressor interacting with RBPJ, CIR1)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57582/cir1-(corepressor-interacting-with-rbpj-cir1)