CLASP2 (cytoplasmic linker associated protein 2)

2018-07-01  

Identity

HGNC
LOCATION
3p22.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 23122
MIM: 605853
HGNC: 17078
Ensembl: ENSG00000163539

Variants:

dbSNP: 23122
ClinVar: 23122
TCGA: ENSG00000163539
COSMIC: CLASP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163539ENST00000313350O75122
ENSG00000163539ENST00000333778E7ENG2
ENSG00000163539ENST00000359576O75122
ENSG00000163539ENST00000399362E7ERI8
ENSG00000163539ENST00000461133E3W994
ENSG00000163539ENST00000468888E7EW49
ENSG00000163539ENST00000475576H7C4M5
ENSG00000163539ENST00000476251H7C4X8
ENSG00000163539ENST00000480013O75122
ENSG00000163539ENST00000480385H7C4I5
ENSG00000163539ENST00000485378D6RBU8
ENSG00000163539ENST00000487200B3KR06
ENSG00000163539ENST00000487553H7C5M8
ENSG00000163539ENST00000496954C9J668
ENSG00000163539ENST00000635664A0A0U1RQI6
ENSG00000163539ENST00000650653J3KR49

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Signaling by Robo receptorREACTOMER-HSA-376176
Role of Abl in Robo-Slit signalingREACTOMER-HSA-428890

References

Pubmed IDYearTitleCitations
365988142023CLASP2 facilitates dynamic actin filament organization along the microtubule lattice.6
365989912023CLASP2 recognizes tubulins exposed at the microtubule plus-end in a nucleotide state-sensitive manner.5
365988142023CLASP2 facilitates dynamic actin filament organization along the microtubule lattice.6
365989912023CLASP2 recognizes tubulins exposed at the microtubule plus-end in a nucleotide state-sensitive manner.5
333720352021SOCS3-microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury.8
345253552021Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration.0
333720352021SOCS3-microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury.8
345253552021Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration.0
317577882020CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments.17
323594302020CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin Incorporation.20
323766232020HIV-1 Exploits CLASP2 To Induce Microtubule Stabilization and Facilitate Virus Trafficking to the Nucleus.14
317577882020CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments.17
323594302020CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin Incorporation.20
323766232020HIV-1 Exploits CLASP2 To Induce Microtubule Stabilization and Facilitate Virus Trafficking to the Nucleus.14
311303432019Significance of CLASP2 expression in prognosis for muscle-invasive bladder cancer patients: A propensity score-based analysis.6

Citation

Dessen P

CLASP2 (cytoplasmic linker associated protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57586/clasp2-(cytoplasmic-linker-associated-protein-2)