FBXL15 (F-box and leucine rich repeat protein 15)

2018-07-01  

Identity

HGNC
FBXL15
LOCATION
10q24.32
LOCUSID
79176
ALIAS
FBXO37,Fbl15,JET,PSD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79176
MIM: 610287
HGNC: 28155
Ensembl: ENSG00000107872

Variants:

dbSNP: 79176
ClinVar: 79176
TCGA: ENSG00000107872
COSMIC: FBXL15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107872ENST00000224862Q9H469
ENSG00000107872ENST00000369956A0A0C4DFV0
ENSG00000107872ENST00000425536X6RGT4
ENSG00000107872ENST00000432590X6RJB2
ENSG00000107872ENST00000440407X6RHD7
ENSG00000107872ENST00000457067X6RCZ8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

References

Pubmed IDYearTitleCitations
282966222017A cell based screening approach for identifying protein degradation regulators.0
282966222017A cell based screening approach for identifying protein degradation regulators.0

Citation

Dessen P

FBXL15 (F-box and leucine rich repeat protein 15)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57589/fbxl15-(f-box-and-leucine-rich-repeat-protein-15)