METRNL (meteorin like, glial cell differentiation regulator)

2018-07-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 284207
MIM: 616241
HGNC: 27584
Ensembl: ENSG00000176845

Variants:

dbSNP: 284207
ClinVar: 284207
TCGA: ENSG00000176845
COSMIC: METRNL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176845ENST00000320095Q641Q3
ENSG00000176845ENST00000570778Q641Q3
ENSG00000176845ENST00000571814Q641Q3
ENSG00000176845ENST00000574053I3L0R0

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381922432024Role of asprosin and meteorin-like peptide in progression of actinic keratosis to squamous cell carcinoma.0
381922432024Role of asprosin and meteorin-like peptide in progression of actinic keratosis to squamous cell carcinoma.0
368125722023Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.12
368253972023Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetes.0
368773552023Is meteorin-like (Metrnl) a novel biomarker to distinguish patients with obstructive sleep apnea (OSA) and patients with OSA at vascular risk.1
380548172023Meteorin-like protein elevation post-exercise improved vascular inflammation among coronary artery disease patients by downregulating NLRP3 inflammasome activity.3
368125722023Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.12
368253972023Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetes.0
368773552023Is meteorin-like (Metrnl) a novel biomarker to distinguish patients with obstructive sleep apnea (OSA) and patients with OSA at vascular risk.1
380548172023Meteorin-like protein elevation post-exercise improved vascular inflammation among coronary artery disease patients by downregulating NLRP3 inflammasome activity.3
357092782022Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase.22
360367492022Decreased serum interleukin-41/Metrnl levels in patients with Graves' disease.5
360846032022Elevated levels of Metrnl in rheumatoid arthritis: Association with disease activity.3
357092782022Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase.22
360367492022Decreased serum interleukin-41/Metrnl levels in patients with Graves' disease.5

Citation

Dessen P

METRNL (meteorin like, glial cell differentiation regulator)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57591/metrnl-(meteorin-like-glial-cell-differentiation-regulator)