METTL7A (methyltransferase like 7A)

2018-07-01  

Identity

HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
AAM-B,AAMB
FUSION GENES

Other Information

Locus ID:

NCBI: 25840
MIM: 618338
HGNC: 24550
Ensembl: ENSG00000185432

Variants:

dbSNP: 25840
ClinVar: 25840
TCGA: ENSG00000185432
COSMIC: METTL7A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185432ENST00000332160Q9H8H3
ENSG00000185432ENST00000332160A0A024R118
ENSG00000185432ENST00000547104Q9H8H3
ENSG00000185432ENST00000547104A0A024R118
ENSG00000185432ENST00000548553Q9H8H3
ENSG00000185432ENST00000548553A0A024R118
ENSG00000185432ENST00000550097H0YI09
ENSG00000185432ENST00000550502F8VQX6

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

References

Pubmed IDYearTitleCitations
381518172024The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors.1
381518172024The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors.1
371761122023A Novel Localization of METTL7A in Bergmann Glial Cells in Human Cerebellum.2
375477172023Transcriptomic characterization revealed that METTL7A inhibits melanoma progression via the p53 signaling pathway and immunomodulatory pathway.1
371761122023A Novel Localization of METTL7A in Bergmann Glial Cells in Human Cerebellum.2
375477172023Transcriptomic characterization revealed that METTL7A inhibits melanoma progression via the p53 signaling pathway and immunomodulatory pathway.1
319558622020Quantitative proteomic analysis identifies novel regulators of methotrexate resistance in choriocarcinoma.22
319558622020Quantitative proteomic analysis identifies novel regulators of methotrexate resistance in choriocarcinoma.22
284167722017DNA methylation of METTL7A gene body regulates its transcriptional level in thyroid cancer.24
284167722017DNA methylation of METTL7A gene body regulates its transcriptional level in thyroid cancer.24
261859862015AAM-B Interacts with Nonstructural 4B and Regulates Hepatitis C Virus Propagation.6
261859862015AAM-B Interacts with Nonstructural 4B and Regulates Hepatitis C Virus Propagation.6

Citation

Dessen P

METTL7A (methyltransferase like 7A)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57592/mettl7a-(methyltransferase-like-7a)