POP4 (POP4 homolog, ribonuclease P/MRP subunit)

2018-11-01  

Identity

HGNC
LOCATION
19q12
LOCUSID
ALIAS
RPP29
FUSION GENES

Other Information

Locus ID:

NCBI: 10775
MIM: 606114
HGNC: 30081
Ensembl: ENSG00000105171

Variants:

dbSNP: 10775
ClinVar: 10775
TCGA: ENSG00000105171
COSMIC: POP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105171ENST00000221770A0A0A0MQS4
ENSG00000105171ENST00000585603O95707
ENSG00000105171ENST00000586420K7ERD7
ENSG00000105171ENST00000586823K7EK50
ENSG00000105171ENST00000590688K7EQV2
ENSG00000105171ENST00000591061K7ESH8

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
RNA transportKEGGko03013
RNA transportKEGGhsa03013
Ribosome biogenesis in eukaryotesKEGGko03008
Ribosome biogenesis in eukaryotesKEGGhsa03008
Gene ExpressionREACTOMER-HSA-74160
tRNA processingREACTOMER-HSA-72306
tRNA processing in the nucleusREACTOMER-HSA-6784531

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
299215822018Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms.9
299215822018Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms.9
278103612017Functional characterization of archaeal homologs of human nuclear RNase P proteins Rpp21 and Rpp29 provides insights into the molecular basis of their cooperativity in catalysis.0
284323562017A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks.15
278103612017Functional characterization of archaeal homologs of human nuclear RNase P proteins Rpp21 and Rpp29 provides insights into the molecular basis of their cooperativity in catalysis.0
284323562017A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks.15
268428932016RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition.15
268428932016RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition.15

Citation

Dessen P

POP4 (POP4 homolog, ribonuclease P/MRP subunit)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57612/pop4-(pop4-homolog-ribonuclease-p-mrp-subunit)