SH3BP1 (SH3 domain binding protein 1)

2018-11-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
ARHGAP43
FUSION GENES

Other Information

Locus ID:

NCBI: 23616
MIM: 617368
HGNC: 10824
Ensembl: ENSG00000100092

Variants:

dbSNP: 23616
ClinVar: 23616
TCGA: ENSG00000100092
COSMIC: SH3BP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100092ENST00000417536Q9Y3L3
ENSG00000100092ENST00000643339A0A2R8Y5V0
ENSG00000100092ENST00000649107A0A3B3IU28
ENSG00000100092ENST00000649765Q9Y3L3
ENSG00000100092ENST00000649765A0A2X0SFX7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
353528782022Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia.2
353528782022Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia.2
287865072018SH3BP1-induced Rac-Wave2 pathway activation regulates cervical cancer cell migration, invasion, and chemoresistance to cisplatin.15
287865072018SH3BP1-induced Rac-Wave2 pathway activation regulates cervical cancer cell migration, invasion, and chemoresistance to cisplatin.15
269339172016SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway.16
269339172016SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway.16
248415632014An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling.17
248415632014An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling.17
232235682013A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation.12
232235682013A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation.12
228912602012Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex.37
228912602012Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex.37

Citation

Dessen P

SH3BP1 (SH3 domain binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57617/sh3bp1-(sh3-domain-binding-protein-1)