MRPL33 (mitochondrial ribosomal protein L33)

2018-11-01  

Identity

HGNC
LOCATION
2p23.2
LOCUSID
ALIAS
C2orf1,L33mt,MRP-L33,RPL33L
FUSION GENES

Other Information

Locus ID:

NCBI: 9553
MIM: 610059
HGNC: 14487
Ensembl: ENSG00000243147

Variants:

dbSNP: 9553
ClinVar: 9553
TCGA: ENSG00000243147
COSMIC: MRPL33

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000243147ENST00000296102O75394
ENSG00000243147ENST00000379666O75394
ENSG00000243147ENST00000448427F8WF37

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
308164922019Isoforms S and L of MRPL33 from alternative splicing have isoform‑specific roles in the chemoresponse to epirubicin in gastric cancer cells via the PI3K/AKT signaling pathway.15
308164922019Isoforms S and L of MRPL33 from alternative splicing have isoform‑specific roles in the chemoresponse to epirubicin in gastric cancer cells via the PI3K/AKT signaling pathway.15
288696072018MRPL33 and its splicing regulator hnRNPK are required for mitochondria function and implicated in tumor progression.28
288696072018MRPL33 and its splicing regulator hnRNPK are required for mitochondria function and implicated in tumor progression.28
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

MRPL33 (mitochondrial ribosomal protein L33)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57622/mrpl33-(mitochondrial-ribosomal-protein-l33)