Identity
HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
ANM,NEM5,STNT,TNT,TNTS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7138
MIM: 191041
HGNC: 11948
Ensembl: ENSG00000105048
Variants:
dbSNP: 7138
ClinVar: 7138
TCGA: ENSG00000105048
COSMIC: TNNT1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Muscle contraction | REACTOME | R-HSA-397014 |
| Striated Muscle Contraction | REACTOME | R-HSA-390522 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38853457 | 2024 | Troponin T1 in tumorigenesis and immune modulation: Insights into multiple cancers and kidney renal clear cell carcinoma. | 1 |
| 38853457 | 2024 | Troponin T1 in tumorigenesis and immune modulation: Insights into multiple cancers and kidney renal clear cell carcinoma. | 1 |
| 36871674 | 2023 | Slow skeletal muscle troponin T acts as a potential prognostic biomarker and therapeutic target for hepatocellular carcinoma. | 1 |
| 37632133 | 2023 | WiTNNess: An international natural history study of infantile-onset TNNT1 myopathy. | 0 |
| 36871674 | 2023 | Slow skeletal muscle troponin T acts as a potential prognostic biomarker and therapeutic target for hepatocellular carcinoma. | 1 |
| 37632133 | 2023 | WiTNNess: An international natural history study of infantile-onset TNNT1 myopathy. | 0 |
| 35053326 | 2022 | Biomarkers-in-Cardiology 8 RE-VISITED-Consistent Safety of Early Discharge with a Dual Marker Strategy Combining a Normal hs-cTnT with a Normal Copeptin in Low-to-Intermediate Risk Patients with Suspected Acute Coronary Syndrome-A Secondary Analysis of the Randomized Biomarkers-in-Cardiology 8 Trial. | 1 |
| 35165004 | 2022 | TNNT1 myopathy with novel compound heterozygous mutations. | 3 |
| 35053326 | 2022 | Biomarkers-in-Cardiology 8 RE-VISITED-Consistent Safety of Early Discharge with a Dual Marker Strategy Combining a Normal hs-cTnT with a Normal Copeptin in Low-to-Intermediate Risk Patients with Suspected Acute Coronary Syndrome-A Secondary Analysis of the Randomized Biomarkers-in-Cardiology 8 Trial. | 1 |
| 35165004 | 2022 | TNNT1 myopathy with novel compound heterozygous mutations. | 3 |
| 32994279 | 2021 | Clinical phenotype and loss of the slow skeletal muscle troponin T in three new patients with recessive TNNT1 nemaline myopathy. | 6 |
| 32994279 | 2021 | Clinical phenotype and loss of the slow skeletal muscle troponin T in three new patients with recessive TNNT1 nemaline myopathy. | 6 |
| 31512553 | 2020 | TNNT1, a prognostic indicator in colon adenocarcinoma, regulates cell behaviors and mediates EMT process. | 13 |
| 31830337 | 2020 | TNNT1, negatively regulated by miR-873, promotes the progression of colorectal cancer. | 17 |
| 31970803 | 2020 | Novel Recessive TNNT1 Congenital Core-Rod Myopathy in French Canadians. | 4 |
Citation
Dessen P
TNNT1 (troponin T1, slow skeletal type)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/57640/gene-fusions-explorer/gene-explorer/
