Identity
HGNC
LOCATION
1q41
LOCUSID
ALIAS
MARK,Par-1c,Par1c
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4139
MIM: 606511
HGNC: 6896
Ensembl: ENSG00000116141
Variants:
dbSNP: 4139
ClinVar: 4139
TCGA: ENSG00000116141
COSMIC: MARK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116141 | ENST00000366917 | Q9P0L2 |
| ENSG00000116141 | ENST00000366918 | Q9P0L2 |
| ENSG00000116141 | ENST00000402574 | B4DIB3 |
| ENSG00000116141 | ENST00000611084 | A0A087X0I6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31281935 | 2019 | MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1. | 7 |
| 31281935 | 2019 | MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1. | 7 |
| 29076440 | 2018 | MARK1 is a Novel Target for miR-125a-5p: Implications for Cell Migration in Cervical Tumor Cells. | 18 |
| 30099988 | 2018 | Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain. | 9 |
| 29076440 | 2018 | MARK1 is a Novel Target for miR-125a-5p: Implications for Cell Migration in Cervical Tumor Cells. | 18 |
| 30099988 | 2018 | Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain. | 9 |
| 27879374 | 2017 | Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase. | 12 |
| 27879374 | 2017 | Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase. | 12 |
| 24243102 | 2014 | Mark/Par-1 marking the polarity of migrating neurons. | 10 |
| 24362629 | 2014 | A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway. | 166 |
| 24243102 | 2014 | Mark/Par-1 marking the polarity of migrating neurons. | 10 |
| 24362629 | 2014 | A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway. | 166 |
| 20158304 | 2010 | A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. | 55 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20158304 | 2010 | A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. | 55 |
Citation
Dessen P
MARK1 (microtubule affinity regulating kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/57662/mark1-(microtubule-affinity-regulating-kinase-1)
