PRELID1 (PRELI domain containing 1)

2018-11-01  

Identity

HGNC
PRELID1
LOCATION
5q35.3
LOCUSID
27166
ALIAS
CGI-106,PRELI,PX19,SBBI12
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27166
MIM: 605733
HGNC: 30255
Ensembl: ENSG00000169230

Variants:

dbSNP: 27166
ClinVar: 27166
TCGA: ENSG00000169230
COSMIC: PRELID1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169230ENST00000303204Q9Y255
ENSG00000169230ENST00000503216Q9Y255
ENSG00000169230ENST00000503853H0YA79
ENSG00000169230ENST00000504594D6REW1
ENSG00000169230ENST00000510797D6RC47

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Transcription of Cell Death GenesREACTOMER-HSA-5633008
TP53 Regulates Transcription of Genes Involved in Cytochrome C ReleaseREACTOMER-HSA-6803204

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
341086212021The pseudogene PRELID1P6 promotes glioma progression via the hnHNPH1-Akt/mTOR axis.8
341086212021The pseudogene PRELID1P6 promotes glioma progression via the hnHNPH1-Akt/mTOR axis.8
308506072019Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins.25
308506072019Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins.25
289121682017Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.12
289121682017Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.12
262756932015Effects of PRELI in Oxidative-Stressed HepG2 Cells.4
262756932015Effects of PRELI in Oxidative-Stressed HepG2 Cells.4
239317592013TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid.96
239317592013TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid.96
226664212012Spare PRELI gene loci: failsafe chromosome insurance?1
226664212012Spare PRELI gene loci: failsafe chromosome insurance?1
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
213646292010Vital function of PRELI and essential requirement of its LEA motif.10
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

PRELID1 (PRELI domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57707/prelid1-(preli-domain-containing-1)