Identity
HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
C20orf21,DF1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54915
MIM: 616529
HGNC: 15867
Ensembl: ENSG00000149658
Variants:
dbSNP: 54915
ClinVar: 54915
TCGA: ENSG00000149658
COSMIC: YTHDF1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000149658 | ENST00000370334 | Q5JXC6 |
| ENSG00000149658 | ENST00000370339 | Q9BYJ9 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37698736 | 2024 | N(6)-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m(6)A/PD-L1 manner. | 6 |
| 37742376 | 2024 | H3K18 lactylation promotes the progression of arsenite-related idiopathic pulmonary fibrosis via YTHDF1/m6A/NREP. | 5 |
| 37983722 | 2024 | YTHDF1 enhances stemness and chemoresistance in triple-negative breast cancer cells by upregulating SIAH2. | 2 |
| 38048860 | 2024 | M6A reader YTHDF1 promotes malignant progression of laryngeal squamous carcinoma through activating the EMT pathway by EIF4A3. | 0 |
| 38147203 | 2024 | The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m(6)A-dependent stabilization of AURKA mRNA. | 0 |
| 38154356 | 2024 | METTL3/YTHDF1 m(6)A axis promotes tumorigenesis by enhancing DDR2 expression in ovarian cancer. | 2 |
| 38241695 | 2024 | N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression. | 2 |
| 38339157 | 2024 | YTHDF1's Regulatory Involvement in Breast Cancer Prognosis, Immunity, and the ceRNA Network. | 1 |
| 38342601 | 2024 | RBMS1 Coordinates with the m(6)A Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation. | 1 |
| 38492220 | 2024 | YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS. | 0 |
| 38551160 | 2024 | YTHDF1 promotes the viability and self‑renewal of glioma stem cells by enhancing LINC00900 stability. | 1 |
| 38683130 | 2024 | YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis. | 0 |
| 39060874 | 2024 | KIAA1429 increases FOXM1 expression through YTHDF1-mediated m6A modification to promote aerobic glycolysis and tumorigenesis in multiple myeloma. | 0 |
| 37698736 | 2024 | N(6)-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m(6)A/PD-L1 manner. | 6 |
| 37742376 | 2024 | H3K18 lactylation promotes the progression of arsenite-related idiopathic pulmonary fibrosis via YTHDF1/m6A/NREP. | 5 |
Citation
Dessen P
YTHDF1 (YTH N6-methyladenosine RNA binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/57717
