Identity
HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
ATFB17,LQT10,Navbeta4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6330
MIM: 608256
HGNC: 10592
Ensembl: ENSG00000177098
Variants:
dbSNP: 6330
ClinVar: 6330
TCGA: ENSG00000177098
COSMIC: SCN4B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177098 | ENST00000324727 | Q8IWT1 |
| ENSG00000177098 | ENST00000324727 | B0YJ93 |
| ENSG00000177098 | ENST00000529878 | Q8IWT1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38678552 | 2024 | Anti-NSCLC role of SCN4B by negative regulation of the cGMP-PKG pathway: Integrated utilization of bioinformatics analysis and in vitro assay validation. | 0 |
| 38678552 | 2024 | Anti-NSCLC role of SCN4B by negative regulation of the cGMP-PKG pathway: Integrated utilization of bioinformatics analysis and in vitro assay validation. | 0 |
| 37826914 | 2023 | SCN4B inhibits the progression of lung adenocarcinoma and is associated with better prognosis. | 1 |
| 37826914 | 2023 | SCN4B inhibits the progression of lung adenocarcinoma and is associated with better prognosis. | 1 |
| 32833340 | 2021 | Silencing of microRNA-3175 represses cell proliferation and invasion in prostate cancer by targeting the potential tumor-suppressor SCN4B. | 4 |
| 34209614 | 2021 | The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells. | 2 |
| 32833340 | 2021 | Silencing of microRNA-3175 represses cell proliferation and invasion in prostate cancer by targeting the potential tumor-suppressor SCN4B. | 4 |
| 34209614 | 2021 | The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells. | 2 |
| 30821358 | 2019 | Significant association of rare variant p.Gly8Ser in cardiac sodium channel β4-subunit SCN4B with atrial fibrillation. | 13 |
| 31020414 | 2019 | Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia. | 3 |
| 30821358 | 2019 | Significant association of rare variant p.Gly8Ser in cardiac sodium channel β4-subunit SCN4B with atrial fibrillation. | 13 |
| 31020414 | 2019 | Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia. | 3 |
| 29723302 | 2018 | Preserved SCN4B expression is an independent indicator of favorable recurrence-free survival in classical papillary thyroid cancer. | 15 |
| 30190309 | 2018 | Structure of the human voltage-gated sodium channel Na(v)1.4 in complex with β1. | 196 |
| 29723302 | 2018 | Preserved SCN4B expression is an independent indicator of favorable recurrence-free survival in classical papillary thyroid cancer. | 15 |
Citation
Dessen P
SCN4B (sodium voltage-gated channel beta subunit 4)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/57725/scn4b-(sodium-voltage-gated-channel-beta-subunit-4)
