PRDM13 (PR/SET domain 13)

2018-11-01  

Identity

HGNC
LOCATION
6q16.2
LOCUSID
ALIAS
MU-MB-20.220,PFM10

Other Information

Locus ID:

NCBI: 59336
MIM: 616741
HGNC: 13998
Ensembl: ENSG00000112238

Variants:

dbSNP: 59336
ClinVar: 59336
TCGA: ENSG00000112238
COSMIC: PRDM13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112238ENST00000369214A0A0A0MRL5
ENSG00000112238ENST00000369215Q9H4Q3

Expression (GTEx)

0
1

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386010162024Two novel non-coding single nucleotide variants in the DNase1 hypersensitivity site of PRDM13 causing North Carolina macular dystrophy in Korea.0
386010162024Two novel non-coding single nucleotide variants in the DNase1 hypersensitivity site of PRDM13 causing North Carolina macular dystrophy in Korea.0
341251592021North Carolina Macular Dystrophy: Phenotypic Variability and Computational Analysis of Disease-Associated Noncoding Variants.7
345267592021A novel duplication involving PRDM13 in a Turkish family supports its role in North Carolina macular dystrophy (NCMD/MCDR1).5
347301122021A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia.12
341251592021North Carolina Macular Dystrophy: Phenotypic Variability and Computational Analysis of Disease-Associated Noncoding Variants.7
345267592021A novel duplication involving PRDM13 in a Turkish family supports its role in North Carolina macular dystrophy (NCMD/MCDR1).5
347301122021A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia.12
324768142020A unique PRDM13-associated variant in a Georgian Jewish family with probable North Carolina macular dystrophy and the possible contribution of a unique CFH variant.8
324768142020A unique PRDM13-associated variant in a Georgian Jewish family with probable North Carolina macular dystrophy and the possible contribution of a unique CFH variant.8
307104612019Unique noncoding variants upstream of PRDM13 are associated with a spectrum of developmental retinal dystrophies including progressive bifocal chorioretinal atrophy.11
307104612019Unique noncoding variants upstream of PRDM13 are associated with a spectrum of developmental retinal dystrophies including progressive bifocal chorioretinal atrophy.11
297672512018Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.4
297672512018Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein.4
277775032016North Carolina macular dystrophy (MCDR1) caused by a novel tandem duplication of the PRDM13 gene.15

Citation

Dessen P

PRDM13 (PR/SET domain 13)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57726/prdm13-(pr-set-domain-13)