Identity
HGNC
LOCATION
5q35.2
LOCUSID
ALIAS
921-L,CPX-2,CPX2,Hfb1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10814
MIM: 605033
HGNC: 2310
Ensembl: ENSG00000145920
Variants:
dbSNP: 10814
ClinVar: 10814
TCGA: ENSG00000145920
COSMIC: CPLX2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Synaptic vesicle cycle | KEGG | ko04721 |
| Synaptic vesicle cycle | KEGG | hsa04721 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38427133 | 2024 | CPLX2 is a novel tumor suppressor and improves the prognosis in glioma. | 0 |
| 38427133 | 2024 | CPLX2 is a novel tumor suppressor and improves the prognosis in glioma. | 0 |
| 36107387 | 2023 | CPLX2 Regulates Ferroptosis and Apoptosis Through NRF2 Pathway in Human Hepatocellular Carcinoma Cells. | 4 |
| 36107387 | 2023 | CPLX2 Regulates Ferroptosis and Apoptosis Through NRF2 Pathway in Human Hepatocellular Carcinoma Cells. | 4 |
| 27866231 | 2017 | Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease. | 21 |
| 27866231 | 2017 | Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease. | 21 |
| 25297695 | 2015 | Complexin2 modulates working memory-related neural activity in patients with schizophrenia. | 9 |
| 25692331 | 2015 | Expression of the synaptic exocytosis-regulating molecule complexin 2 in taste buds and its participation in peripheral taste transduction. | 4 |
| 25297695 | 2015 | Complexin2 modulates working memory-related neural activity in patients with schizophrenia. | 9 |
| 25692331 | 2015 | Expression of the synaptic exocytosis-regulating molecule complexin 2 in taste buds and its participation in peripheral taste transduction. | 4 |
| 25564026 | 2014 | Risk and protective effects of the complexin-2 gene and gene-environment interactions in schizophrenia. | 1 |
| 25564026 | 2014 | Risk and protective effects of the complexin-2 gene and gene-environment interactions in schizophrenia. | 1 |
| 19851296 | 2010 | Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. | 7 |
| 20198315 | 2010 | Association of genetic variants with hemorrhagic stroke in Japanese individuals. | 17 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
CPLX2 (complexin 2)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/57731/gene-fusions/deep-insight-explorer/
