ETFB (electron transfer flavoprotein subunit beta)

2018-11-01  

Identity

HGNC
LOCATION
19q13.41
LOCUSID
ALIAS
FP585,MADD
FUSION GENES

Other Information

Locus ID:

NCBI: 2109
MIM: 130410
HGNC: 3482
Ensembl: ENSG00000105379

Variants:

dbSNP: 2109
ClinVar: 2109
TCGA: ENSG00000105379
COSMIC: ETFB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105379ENST00000309244P38117
ENSG00000105379ENST00000354232P38117
ENSG00000105379ENST00000596253M0QY67

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Respiratory electron transportREACTOMER-HSA-611105
Protein methylationREACTOMER-HSA-8876725

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
314183422019Molecular and Clinical Investigations on Portuguese Patients with Multiple acyl-CoA Dehydrogenase Deficiency.5
316656002019Molecular Oxygen Binding in the Mitochondrial Electron Transfer Flavoprotein.10
314183422019Molecular and Clinical Investigations on Portuguese Patients with Multiple acyl-CoA Dehydrogenase Deficiency.5
316656002019Molecular Oxygen Binding in the Mitochondrial Electron Transfer Flavoprotein.10
289137292018Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.22
293019332018Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein.9
289137292018Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients.22
293019332018Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein.9
270358692016The decreased expression of electron transfer flavoprotein β is associated with tubular cell apoptosis in diabetic nephropathy.7
278409372016ATP5B and ETFB metabolic markers in children with congenital hydronephrosis.2
270358692016The decreased expression of electron transfer flavoprotein β is associated with tubular cell apoptosis in diabetic nephropathy.7
278409372016ATP5B and ETFB metabolic markers in children with congenital hydronephrosis.2
254167812015Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity.34
259155192015Electron Transfer Flavoprotein Subunit Beta Is a Candidate Endothelial Cell Autoantigen in Behçet's Disease.5
254167812015Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity.34

Citation

Dessen P

ETFB (electron transfer flavoprotein subunit beta)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57737/gene-fusions/deep-insight-explorer/