TROAP (trophinin associated protein)

2018-11-01  

Identity

HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
TASTIN
FUSION GENES

Other Information

Locus ID:

NCBI: 10024
MIM: 603872
HGNC: 12327
Ensembl: ENSG00000135451

Variants:

dbSNP: 10024
ClinVar: 10024
TCGA: ENSG00000135451
COSMIC: TROAP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135451ENST00000257909Q12815
ENSG00000135451ENST00000380327Q12815
ENSG00000135451ENST00000546735F8VR46
ENSG00000135451ENST00000546776F8VVT5
ENSG00000135451ENST00000547807F8W1E3
ENSG00000135451ENST00000547923F8W1U0
ENSG00000135451ENST00000548311Q12815
ENSG00000135451ENST00000549275F8VVX4
ENSG00000135451ENST00000549534F8VXV6
ENSG00000135451ENST00000549891F8VR46
ENSG00000135451ENST00000550346F8VVS4
ENSG00000135451ENST00000550709F8VXF3
ENSG00000135451ENST00000551192B7Z5Q9
ENSG00000135451ENST00000551245F8W130
ENSG00000135451ENST00000551567F8W052

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366913322023Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways.3
372986092023TROAP Promotes the Proliferation, Migration, and Metastasis of Kidney Renal Clear Cell Carcinoma with the Help of STAT3.2
376080332023METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway.2
366913322023Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways.3
372986092023TROAP Promotes the Proliferation, Migration, and Metastasis of Kidney Renal Clear Cell Carcinoma with the Help of STAT3.2
376080332023METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway.2
335003842021TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression.18
342870992021MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.9
335003842021TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression.18
342870992021MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.9
302846522019High Trophinin-Associated Protein Expression Is an Independent Predictor of Poor Survival in Liver Cancer.40
304311202019TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways.18
311987872019TROAP Promotes Breast Cancer Proliferation and Metastasis.15
302846522019High Trophinin-Associated Protein Expression Is an Independent Predictor of Poor Survival in Liver Cancer.40
304311202019TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways.18

Citation

Dessen P

TROAP (trophinin associated protein)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57747/gene-fusions-explorer/