Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56907
MIM: 609216
HGNC: 30622
Ensembl: ENSG00000134278
Variants:
dbSNP: 56907
ClinVar: 56907
TCGA: ENSG00000134278
COSMIC: SPIRE1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Dorso-ventral axis formation | KEGG | ko04320 |
| Dorso-ventral axis formation | KEGG | hsa04320 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34863993 | 2022 | Lnc-SMaRT Translational Regulation of Spire1, A New Player in Muscle Differentiation. | 1 |
| 35084586 | 2022 | Spire1 and Myosin Vc promote Ca(2+)-evoked externalization of von Willebrand factor in endothelial cells. | 4 |
| 34863993 | 2022 | Lnc-SMaRT Translational Regulation of Spire1, A New Player in Muscle Differentiation. | 1 |
| 35084586 | 2022 | Spire1 and Myosin Vc promote Ca(2+)-evoked externalization of von Willebrand factor in endothelial cells. | 4 |
| 26668326 | 2016 | Role of the C-terminal Extension of Formin 2 in Its Activation by Spire Protein and Processive Assembly of Actin Filaments. | 4 |
| 27627128 | 2016 | A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. | 10 |
| 26668326 | 2016 | Role of the C-terminal Extension of Formin 2 in Its Activation by Spire Protein and Processive Assembly of Actin Filaments. | 4 |
| 27627128 | 2016 | A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. | 10 |
| 26287480 | 2015 | DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected]. | 109 |
| 26305500 | 2015 | A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division. | 161 |
| 26287480 | 2015 | DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected]. | 109 |
| 26305500 | 2015 | A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division. | 161 |
| 24213528 | 2014 | Spire-1 contributes to the invadosome and its associated invasive properties. | 17 |
| 24586110 | 2014 | Spire and Formin 2 synergize and antagonize in regulating actin assembly in meiosis by a ping-pong mechanism. | 43 |
| 24213528 | 2014 | Spire-1 contributes to the invadosome and its associated invasive properties. | 17 |
Citation
Dessen P
SPIRE1 (spire type actin nucleation factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/57756/spire1-(spire-type-actin-nucleation-factor-1)
