Identity
HGNC
LOCATION
1q24.1
LOCUSID
ALIAS
HP10122,PCIA3,PNAS-136,TMCC4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54499
MIM: 614123
HGNC: 18188
Ensembl: ENSG00000143183
Variants:
dbSNP: 54499
ClinVar: 54499
TCGA: ENSG00000143183
COSMIC: TMCO1
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38372107 | 2024 | TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance. | 0 |
| 38372107 | 2024 | TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance. | 0 |
| 36708876 | 2023 | Craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome-1 in two new patients with the same homozygous TMCO1 variant and review of the literature. | 0 |
| 37527660 | 2023 | Repeat polymorphisms underlie top genetic risk loci for glaucoma and colorectal cancer. | 7 |
| 36708876 | 2023 | Craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome-1 in two new patients with the same homozygous TMCO1 variant and review of the literature. | 0 |
| 37527660 | 2023 | Repeat polymorphisms underlie top genetic risk loci for glaucoma and colorectal cancer. | 7 |
| 35121659 | 2022 | iASPP suppresses Gp78-mediated TMCO1 degradation to maintain Ca(2+) homeostasis and control tumor growth and drug resistance. | 3 |
| 35121659 | 2022 | iASPP suppresses Gp78-mediated TMCO1 degradation to maintain Ca(2+) homeostasis and control tumor growth and drug resistance. | 3 |
| 30556256 | 2019 | Cerebrofaciothoracic dysplasia: Four new patients with a recurrent TMCO1 pathogenic variant. | 4 |
| 30862618 | 2019 | SNP located in an AluJb repeat downstream of TMCO1, rs4657473, is protective for POAG in African Americans. | 6 |
| 30926762 | 2019 | Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression. | 35 |
| 30962442 | 2019 | TMCO1-mediated Ca(2+) leak underlies osteoblast functions via CaMKII signaling. | 25 |
| 31102500 | 2019 | A novel biallelic loss-of-function mutation in TMCO1 gene confirming and expanding the phenotype spectrum of cerebro-facio-thoracic dysplasia. | 5 |
| 30556256 | 2019 | Cerebrofaciothoracic dysplasia: Four new patients with a recurrent TMCO1 pathogenic variant. | 4 |
| 30862618 | 2019 | SNP located in an AluJb repeat downstream of TMCO1, rs4657473, is protective for POAG in African Americans. | 6 |
Citation
Dessen P
TMCO1 (transmembrane and coiled-coil domains 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/57757/
