CCN3 (cellular communication network factor 3)

2018-11-01  

Identity

HGNC
LOCATION
8q24.12
LOCUSID
ALIAS
IBP-9,IGFBP-9,IGFBP9,NOV,NOVh

Other Information

Locus ID:

NCBI: 4856
MIM: 164958
HGNC: 7885
Ensembl: ENSG00000136999

Variants:

dbSNP: 4856
ClinVar: 4856
TCGA: ENSG00000136999
COSMIC: CCN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136999ENST00000259526P48745
ENSG00000136999ENST00000259526A0A024R9J4

References

Pubmed IDYearTitleCitations
120501622002The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway.70
126955222003CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family.67
151810162004Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells.47
156110782005Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing.46
158247362005In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type.44
118911842002The expression of ccn3(nov) gene in musculoskeletal tumors.40
174632872007NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells.40
201393552010CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration.37
179683132008Downregulation of CCN3 expression as a potential mechanism for melanoma progression.36
179683132008Downregulation of CCN3 expression as a potential mechanism for melanoma progression.36

Citation

Dessen P

CCN3 (cellular communication network factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57759/ccn3-(cellular-communication-network-factor-3)