TMEM165 (transmembrane protein 165)

2018-12-01  

Identity

HGNC
LOCATION
4q12
LOCUSID
ALIAS
CDG2K,FT27,GDT1,SLC64A1,TMPT27,TPARL
FUSION GENES

Other Information

Locus ID:

NCBI: 55858
MIM: 614726
HGNC: 30760
Ensembl: ENSG00000134851

Variants:

dbSNP: 55858
ClinVar: 55858
TCGA: ENSG00000134851
COSMIC: TMEM165

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134851ENST00000381334Q9HC07
ENSG00000134851ENST00000506103V9GYC8
ENSG00000134851ENST00000506198D6RD79
ENSG00000134851ENST00000508404D6RBL0
ENSG00000134851ENST00000608091V9GY93

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370624522023Insights into the regulation of cellular Mn(2+) homeostasis via TMEM165.1
370624522023Insights into the regulation of cellular Mn(2+) homeostasis via TMEM165.1
314151122020Fetal bovine serum impacts the observed N-glycosylation defects in TMEM165 KO HEK cells.8
320471082020The human Golgi protein TMEM165 transports calcium and manganese in yeast and bacterial cells.22
327007712020Serum bikunin isoforms in congenital disorders of glycosylation and linkeropathies.10
314151122020Fetal bovine serum impacts the observed N-glycosylation defects in TMEM165 KO HEK cells.8
320471082020The human Golgi protein TMEM165 transports calcium and manganese in yeast and bacterial cells.22
327007712020Serum bikunin isoforms in congenital disorders of glycosylation and linkeropathies.10
313510902019Dissection of TMEM165 function in Golgi glycosylation and its Mn(2+) sensitivity.11
316523052019Investigating the functional link between TMEM165 and SPCA1.7
313510902019Dissection of TMEM165 function in Golgi glycosylation and its Mn(2+) sensitivity.11
316523052019Investigating the functional link between TMEM165 and SPCA1.7
300158982018TMEM165, a Golgi transmembrane protein, is a novel marker for hepatocellular carcinoma and its depletion impairs invasion activity.10
300158982018TMEM165, a Golgi transmembrane protein, is a novel marker for hepatocellular carcinoma and its depletion impairs invasion activity.10
274011452017TMEM165 deficiencies in Congenital Disorders of Glycosylation type II (CDG-II): Clues and evidences for roles of the protein in Golgi functions and ion homeostasis.20

Citation

Dessen P

TMEM165 (transmembrane protein 165)

Atlas Genet Cytogenet Oncol Haematol. 2018-12-01

Online version: http://atlasgeneticsoncology.org/gene/57768/tmem165-(transmembrane-protein-165)