RHCG (Rh family C glycoprotein)

2018-12-01  

Identity

HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
C15orf6,PDRC2,RHGK,SLC42A3
FUSION GENES

Other Information

Locus ID:

NCBI: 51458
MIM: 605381
HGNC: 18140
Ensembl: ENSG00000140519

Variants:

dbSNP: 51458
ClinVar: 51458
TCGA: ENSG00000140519
COSMIC: RHCG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140519ENST00000268122Q9UBD6
ENSG00000140519ENST00000558030H0YKQ3
ENSG00000140519ENST00000558184H0YMS1
ENSG00000140519ENST00000558360H0YM79
ENSG00000140519ENST00000560081H0YMF8
ENSG00000140519ENST00000649642A0A3B3IT41

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Rhesus glycoproteins mediate ammonium transport.REACTOMER-HSA-444411

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
376644502023Comprehensive Analysis to Identify Rh Family C Glycoprotein (RHCG) as the Causative Gene for Psoriasis and Search for Alternative Treatment Modalities.1
376644502023Comprehensive Analysis to Identify Rh Family C Glycoprotein (RHCG) as the Causative Gene for Psoriasis and Search for Alternative Treatment Modalities.1
317563122020High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline.2
317563122020High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline.2
311700902019Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.3
311700902019Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.3
290545312018The ammonia transporter RhCG modulates urinary acidification by interacting with the vacuolar proton-ATPases in renal intercalated cells.9
292908012018RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression.21
298521772018RHCG suppresses cervical cancer progression through inhibiting migration and inducing apoptosis regulated by TGF-β1.6
290545312018The ammonia transporter RhCG modulates urinary acidification by interacting with the vacuolar proton-ATPases in renal intercalated cells.9
292908012018RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression.21
298521772018RHCG suppresses cervical cancer progression through inhibiting migration and inducing apoptosis regulated by TGF-β1.6
261905732015Mechanism of NH4(+) Recruitment and NH3 Transport in Rh Proteins.9
261905732015Mechanism of NH4(+) Recruitment and NH3 Transport in Rh Proteins.9
246477132014Ammonia transport in the kidney by Rhesus glycoproteins.34

Citation

Dessen P

RHCG (Rh family C glycoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2018-12-01

Online version: http://atlasgeneticsoncology.org/gene/57771/rhcg-(rh-family-c-glycoprotein)