Identity
HGNC
LOCATION
3q21.2
LOCUSID
ALIAS
HEG,MST112,MSTP112
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57493
MIM: 614182
HGNC: 29227
Ensembl: ENSG00000173706
Variants:
dbSNP: 57493
ClinVar: 57493
TCGA: ENSG00000173706
COSMIC: HEG1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000173706 | ENST00000311127 | Q9ULI3 |
| ENSG00000173706 | ENST00000477536 | A0A2R8Y4Z1 |
| ENSG00000173706 | ENST00000482699 | H7C4K2 |
| ENSG00000173706 | ENST00000487661 | H7C4M4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38099436 | 2024 | HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells. | 2 |
| 38099436 | 2024 | HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells. | 2 |
| 33774129 | 2021 | LncRNA SNHG12 promotes proliferation and epithelial mesenchymal transition in hepatocellular carcinoma through targeting HEG1 via miR-516a-5p. | 6 |
| 34240508 | 2021 | Membranous HEG1 expression is a useful marker in the differential diagnosis of epithelioid and biphasic malignant mesothelioma versus carcinomas. | 3 |
| 33774129 | 2021 | LncRNA SNHG12 promotes proliferation and epithelial mesenchymal transition in hepatocellular carcinoma through targeting HEG1 via miR-516a-5p. | 6 |
| 34240508 | 2021 | Membranous HEG1 expression is a useful marker in the differential diagnosis of epithelioid and biphasic malignant mesothelioma versus carcinomas. | 3 |
| 32205484 | 2020 | HEG1 Is a Highly Specific and Sensitive Marker of Epithelioid Malignant Mesothelioma. | 6 |
| 32284171 | 2020 | HEG1-responsive microRNA-23b regulates cell proliferation in malignant mesothelioma cells. | 4 |
| 32205484 | 2020 | HEG1 Is a Highly Specific and Sensitive Marker of Epithelioid Malignant Mesothelioma. | 6 |
| 32284171 | 2020 | HEG1-responsive microRNA-23b regulates cell proliferation in malignant mesothelioma cells. | 4 |
| 31278131 | 2019 | HEG1 indicates poor prognosis and promotes hepatocellular carcinoma invasion, metastasis, and EMT by activating Wnt/β-catenin signaling. | 33 |
| 31278131 | 2019 | HEG1 indicates poor prognosis and promotes hepatocellular carcinoma invasion, metastasis, and EMT by activating Wnt/β-catenin signaling. | 33 |
| 30250045 | 2018 | Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1. | 8 |
| 30250045 | 2018 | Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1. | 8 |
| 28361969 | 2017 | HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma. | 21 |
Citation
Dessen P
HEG1 (heart development protein with EGF like domains 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-12-01
Online version: http://atlasgeneticsoncology.org/gene/57772/heg1-(heart-development-protein-with-egf-like-domains-1)
