Identity
HGNC
LOCATION
1p13.3
LOCUSID
ALIAS
ADGRC2,CDHF10,EGFL2,Flamingo1,MEGF3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1952
MIM: 604265
HGNC: 3231
Ensembl: ENSG00000143126
Variants:
dbSNP: 1952
ClinVar: 1952
TCGA: ENSG00000143126
COSMIC: CELSR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143126 | ENST00000271332 | Q9HCU4 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA133950441 | hmg coa reductase inhibitors | Chemical | ClinicalAnnotation | associated | PD | 25350695 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37224017 | 2023 | The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms. | 3 |
| 37224017 | 2023 | The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms. | 3 |
| 34983065 | 2022 | Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human. | 2 |
| 34983065 | 2022 | Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human. | 2 |
| 33810964 | 2021 | rs629301 CELSR2 polymorphism confers a ten-year equivalent risk of critical stenosis assessed by coronary angiography. | 6 |
| 34478580 | 2021 | CELSR2 deficiency suppresses lipid accumulation in hepatocyte by impairing the UPR and elevating ROS level. | 7 |
| 33810964 | 2021 | rs629301 CELSR2 polymorphism confers a ten-year equivalent risk of critical stenosis assessed by coronary angiography. | 6 |
| 34478580 | 2021 | CELSR2 deficiency suppresses lipid accumulation in hepatocyte by impairing the UPR and elevating ROS level. | 7 |
| 32293343 | 2020 | Identification of CELSR2 as a novel prognostic biomarker for hepatocellular carcinoma. | 9 |
| 32293343 | 2020 | Identification of CELSR2 as a novel prognostic biomarker for hepatocellular carcinoma. | 9 |
| 29489009 | 2018 | Differential cellular localization of CELSR2 and ING4 and correlations with hormone receptor status in breast cancer. | 9 |
| 29489009 | 2018 | Differential cellular localization of CELSR2 and ING4 and correlations with hormone receptor status in breast cancer. | 9 |
| 28052552 | 2017 | CELSR2, encoding a planar cell polarity protein, is a putative gene in Joubert syndrome with cortical heterotopia, microophthalmia, and growth hormone deficiency. | 13 |
| 29240829 | 2017 | CELSR2 is a candidate susceptibility gene in idiopathic scoliosis. | 10 |
| 28052552 | 2017 | CELSR2, encoding a planar cell polarity protein, is a putative gene in Joubert syndrome with cortical heterotopia, microophthalmia, and growth hormone deficiency. | 13 |
Citation
Dessen P
CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2018-12-01
Online version: http://atlasgeneticsoncology.org/gene/57777/celsr2-(cadherin-egf-lag-seven-pass-g-type-receptor-2)
