TSPAN15 (tetraspanin 15)

2018-12-01  

Identity

HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
2700063A19Rik,NET-7,NET7,TM4SF15
FUSION GENES

Other Information

Locus ID:

NCBI: 23555
MIM: 613140
HGNC: 23298
Ensembl: ENSG00000099282

Variants:

dbSNP: 23555
ClinVar: 23555
TCGA: ENSG00000099282
COSMIC: TSPAN15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099282ENST00000373290O95858
ENSG00000099282ENST00000452130H7C285

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
347398412022Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site.8
347398412022Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site.8
321117352020The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex.21
321117352020The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex.21
313906802019Tspan15 Is a New Stemness-Related Marker in Hepatocellular Carcinoma.13
315185582019Tspan15 plays a crucial role in metastasis in oral squamous cell carcinoma.9
313906802019Tspan15 Is a New Stemness-Related Marker in Hepatocellular Carcinoma.13
315185582019Tspan15 plays a crucial role in metastasis in oral squamous cell carcinoma.9
296509642018TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling.43
296509642018TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling.43
257729352015Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.130
257729352015Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.130
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83

Citation

Dessen P

TSPAN15 (tetraspanin 15)

Atlas Genet Cytogenet Oncol Haematol. 2018-12-01

Online version: http://atlasgeneticsoncology.org/gene/57780/tspan15-(tetraspanin-15)