TMEM59 (transmembrane protein 59)

2019-04-01  

Identity

HGNC
TMEM59
LOCATION
1p32.3
LOCUSID
9528
ALIAS
C1orf8,DCF1,HSPC001,PRO195,UNQ169
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9528
MIM: 617084
HGNC: 1239
Ensembl: ENSG00000116209

Variants:

dbSNP: 9528
ClinVar: 9528
TCGA: ENSG00000116209
COSMIC: TMEM59

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116209ENST00000234831Q9BXS4
ENSG00000116209ENST00000371337Q5T703
ENSG00000116209ENST00000371341Q5T6Z8
ENSG00000116209ENST00000371344Q5T6Z8
ENSG00000116209ENST00000371348Q5T6Z8
ENSG00000116209ENST00000420738Q5T706
ENSG00000116209ENST00000440019Q5T706
ENSG00000116209ENST00000452421Q5T704

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
347999922022Dcf1 induces glioblastoma cells apoptosis by blocking autophagy.2
354266172022CircTMEM59 Serves as miR-410-3p Sponge to Inhibit the Proliferation and Metastasis of Colorectal Cancer by Regulating HOXD8.4
347999922022Dcf1 induces glioblastoma cells apoptosis by blocking autophagy.2
354266172022CircTMEM59 Serves as miR-410-3p Sponge to Inhibit the Proliferation and Metastasis of Colorectal Cancer by Regulating HOXD8.4
325400982020Dcf1 alleviates C99-mediated deficits in drosophila by reducing the cleavage of C99.1
330552162020The Chlamydia effector CT622/TaiP targets a nonautophagy related function of ATG16L1.12
325400982020Dcf1 alleviates C99-mediated deficits in drosophila by reducing the cleavage of C99.1
330552162020The Chlamydia effector CT622/TaiP targets a nonautophagy related function of ATG16L1.12
303651232019Dendritic cell factor 1 inhibits proliferation and migration and induces apoptosis of neuroblastoma cells by inhibiting the ERK signaling pathway.3
303651232019Dendritic cell factor 1 inhibits proliferation and migration and induces apoptosis of neuroblastoma cells by inhibiting the ERK signaling pathway.3
290743932018DCF1 subcellular localization and its function in mitochondria.3
296322102018TMEM59 potentiates Wnt signaling by promoting signalosome formation.22
290743932018DCF1 subcellular localization and its function in mitochondria.3
296322102018TMEM59 potentiates Wnt signaling by promoting signalosome formation.22
224513122012Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex.122

Citation

Dessen P

TMEM59 (transmembrane protein 59)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57792/tmem59-(transmembrane-protein-59)