Identity
HGNC
LOCATION
17q12
LOCUSID
ALIAS
CAB1,CACNLB1,CCHLB1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 782
MIM: 114207
HGNC: 1401
Ensembl: ENSG00000067191
Variants:
dbSNP: 782
ClinVar: 782
TCGA: ENSG00000067191
COSMIC: CACNB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000067191 | ENST00000344140 | Q02641 |
| ENSG00000067191 | ENST00000394303 | Q02641 |
| ENSG00000067191 | ENST00000394310 | Q02641 |
| ENSG00000067191 | ENST00000622445 | Q6TME4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448871 | celecoxib | Chemical | Pathway | associated | 22336956 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29212769 | 2018 | Functional and structural characterization of a novel malignant hyperthermia-susceptible variant of DHPR-β(1a) subunit (CACNB1). | 2 |
| 29212769 | 2018 | Functional and structural characterization of a novel malignant hyperthermia-susceptible variant of DHPR-β(1a) subunit (CACNB1). | 2 |
| 27129199 | 2016 | Fluorescence Resonance Energy Transfer-based Structural Analysis of the Dihydropyridine Receptor α1S Subunit Reveals Conformational Differences Induced by Binding of the β1a Subunit. | 0 |
| 27129199 | 2016 | Fluorescence Resonance Energy Transfer-based Structural Analysis of the Dihydropyridine Receptor α1S Subunit Reveals Conformational Differences Induced by Binding of the β1a Subunit. | 0 |
| 19821165 | 2010 | Inactivation of L-type calcium channels is determined by the length of the N terminus of mutant beta(1) subunits. | 12 |
| 21098446 | 2010 | MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation. | 181 |
| 19821165 | 2010 | Inactivation of L-type calcium channels is determined by the length of the N terminus of mutant beta(1) subunits. | 12 |
| 21098446 | 2010 | MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation. | 181 |
Citation
Dessen P
CACNB1 (calcium voltage-gated channel auxiliary subunit beta 1)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57793/cacnb1-(calcium-voltage-gated-channel-auxiliary-subunit-beta-1)
