NFE2L3 (nuclear factor, erythroid 2 like 3)

2019-04-01  

Identity

HGNC
LOCATION
7p15.2
LOCUSID
ALIAS
NRF3

Other Information

Locus ID:

NCBI: 9603
MIM: 604135
HGNC: 7783
Ensembl: ENSG00000050344

Variants:

dbSNP: 9603
ClinVar: 9603
TCGA: ENSG00000050344
COSMIC: NFE2L3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000050344ENST00000056233Q9Y4A8
ENSG00000050344ENST00000607375U3KQ19

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370713042024Hypomethylation-Mediated Upregulation of NFE2L3 Promotes Malignant Phenotypes of Clear Cell Renal Cell Carcinoma Cells.1
385144882024Identification roles of NFE2L3 in digestive system cancers.0
370713042024Hypomethylation-Mediated Upregulation of NFE2L3 Promotes Malignant Phenotypes of Clear Cell Renal Cell Carcinoma Cells.1
385144882024Identification roles of NFE2L3 in digestive system cancers.0
378079682023NRF3 suppresses squamous carcinogenesis, involving the unfolded protein response regulator HSPA5.1
378079682023NRF3 suppresses squamous carcinogenesis, involving the unfolded protein response regulator HSPA5.1
350226602022NFE2L3 promotes tumor progression and predicts a poor prognosis of bladder cancer.5
361085712022Transcription factor NFE2L3 promotes the proliferation of esophageal squamous cell carcinoma cells and causes radiotherapy resistance by regulating IL-6.2
363378402022NFE2L3 as a Potential Functional Gene Regulating Immune Microenvironment in Human Kidney Cancer.1
350226602022NFE2L3 promotes tumor progression and predicts a poor prognosis of bladder cancer.5
361085712022Transcription factor NFE2L3 promotes the proliferation of esophageal squamous cell carcinoma cells and causes radiotherapy resistance by regulating IL-6.2
363378402022NFE2L3 as a Potential Functional Gene Regulating Immune Microenvironment in Human Kidney Cancer.1
347833042021Elevated expression of NFE2L3 promotes the development of gastric cancer through epithelial-mesenchymal transformation.3
347833042021Elevated expression of NFE2L3 promotes the development of gastric cancer through epithelial-mesenchymal transformation.3
321230082020NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein.20

Citation

Dessen P

NFE2L3 (nuclear factor, erythroid 2 like 3)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57808/nfe2l3-(nuclear-factor-erythroid-2-like-3)