SLC5A10 (solute carrier family 5 member 10)

2019-04-01  

Identity

HGNC
SLC5A10
LOCATION
17p11.2
LOCUSID
125206
ALIAS
SGLT-5,SGLT5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 125206
MIM: 618636
HGNC: 23155
Ensembl: ENSG00000154025

Variants:

dbSNP: 125206
ClinVar: 125206
TCGA: ENSG00000154025
COSMIC: SLC5A10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154025ENST00000317977A0PJK1
ENSG00000154025ENST00000395643A0PJK1
ENSG00000154025ENST00000395645A0PJK1
ENSG00000154025ENST00000395647A0PJK1
ENSG00000154025ENST00000417251A0PJK1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Hexose transportREACTOMER-HSA-189200
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
375945492023SGLT5 is the renal transporter for 1,5-anhydroglucitol, a major player in two rare forms of neutropenia.4
375945492023SGLT5 is the renal transporter for 1,5-anhydroglucitol, a major player in two rare forms of neutropenia.4
309760182019Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study.7
309760182019Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study.7
302818722018Functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small-cell lung cancer.9
302818722018Functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small-cell lung cancer.9
245730862014Fingerprints of hSGLT5 sugar and cation selectivity.4
245730862014Fingerprints of hSGLT5 sugar and cation selectivity.4
222127182012Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter.37
222127182012Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter.37

Citation

Dessen P

SLC5A10 (solute carrier family 5 member 10)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57810/slc5a10-(solute-carrier-family-5-member-10)