Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 92359
MIM: 609737
HGNC: 20237
Ensembl: ENSG00000130545
Variants:
dbSNP: 92359
ClinVar: 92359
TCGA: ENSG00000130545
COSMIC: CRB3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130545 | ENST00000308243 | Q9BUF7 |
| ENSG00000130545 | ENST00000356762 | Q9BUF7 |
| ENSG00000130545 | ENST00000598494 | Q9BUF7 |
| ENSG00000130545 | ENST00000600229 | Q9BUF7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38049890 | 2023 | Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3). | 2 |
| 38049890 | 2023 | Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3). | 2 |
| 33903236 | 2021 | Aberrant epithelial polarity cues drive the development of precancerous airway lesions. | 6 |
| 33903236 | 2021 | Aberrant epithelial polarity cues drive the development of precancerous airway lesions. | 6 |
| 30980524 | 2019 | Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1. | 3 |
| 31087799 | 2019 | Crumbs protein homolog 3 (CRB3) expression is associated with oestrogen and progesterone receptor positivity in breast cancer. | 2 |
| 31147860 | 2019 | DNA methylation of CRB3 is a prognostic biomarker in clear cell renal cell carcinoma. | 6 |
| 31391273 | 2019 | A CRISPR Screen Identifies the Cell Polarity Determinant Crumbs 3 as an Adeno-associated Virus Restriction Factor in Hepatocytes. | 9 |
| 31500807 | 2019 | Crumbs3 regulates the expression of glycosphingolipids on the plasma membrane to promote colon cancer cell migration. | 6 |
| 30980524 | 2019 | Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1. | 3 |
| 31087799 | 2019 | Crumbs protein homolog 3 (CRB3) expression is associated with oestrogen and progesterone receptor positivity in breast cancer. | 2 |
| 31147860 | 2019 | DNA methylation of CRB3 is a prognostic biomarker in clear cell renal cell carcinoma. | 6 |
| 31391273 | 2019 | A CRISPR Screen Identifies the Cell Polarity Determinant Crumbs 3 as an Adeno-associated Virus Restriction Factor in Hepatocytes. | 9 |
| 31500807 | 2019 | Crumbs3 regulates the expression of glycosphingolipids on the plasma membrane to promote colon cancer cell migration. | 6 |
| 29602199 | 2018 | Elevated CRB3 expression suppresses breast cancer stemness by inhibiting β-catenin signalling to restore tamoxifen sensitivity. | 14 |
Citation
Dessen P
CRB3 (crumbs cell polarity complex component 3)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57811/crb3-(crumbs-cell-polarity-complex-component-3)
