Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54664
MIM: 613413
HGNC: 22407
Ensembl: ENSG00000106460
Variants:
dbSNP: 54664
ClinVar: 54664
TCGA: ENSG00000106460
COSMIC: TMEM106B
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38232138 | 2024 | TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. | 4 |
| 38674351 | 2024 | Association of TMEM106B with Cortical APOE Gene Expression in Neurodegenerative Conditions. | 0 |
| 38710967 | 2024 | Physiological and pathological functions of TMEM106B in neurodegenerative diseases. | 0 |
| 38924247 | 2024 | A common Alu insertion in the 3'UTR of TMEM106B is associated with risk of dementia. | 1 |
| 38232138 | 2024 | TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. | 4 |
| 38674351 | 2024 | Association of TMEM106B with Cortical APOE Gene Expression in Neurodegenerative Conditions. | 0 |
| 38710967 | 2024 | Physiological and pathological functions of TMEM106B in neurodegenerative diseases. | 0 |
| 38924247 | 2024 | A common Alu insertion in the 3'UTR of TMEM106B is associated with risk of dementia. | 1 |
| 36527486 | 2023 | Accumulation of TMEM106B C-terminal fragments in neurodegenerative disease and aging. | 22 |
| 37100087 | 2023 | C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes. | 8 |
| 37129766 | 2023 | Superresolution live-cell imaging reveals that the localization of TMEM106B to filopodia in oligodendrocytes is compromised by the hypomyelination-related D252N mutation. | 0 |
| 37421949 | 2023 | TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry. | 30 |
| 37530644 | 2023 | TMEM106B Fibrils from FTLD Patients and Healthy Controls. | 0 |
| 37563705 | 2023 | TMEM106B aggregation in neurodegenerative diseases: linking genetics to function. | 3 |
| 37726834 | 2023 | The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus. | 9 |
Citation
Dessen P
TMEM106B (transmembrane protein 106B)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57836/tmem106b-(transmembrane-protein-106b)
