TEN1 (TEN1 subunit of CST complex)

2019-04-01  

Identity

HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
C17orf106
FUSION GENES

Other Information

Locus ID:

NCBI: 100134934
MIM: 613130
HGNC: 37242
Ensembl: ENSG00000257949

Variants:

dbSNP: 100134934
ClinVar: 100134934
TCGA: ENSG00000257949
COSMIC: TEN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000257949ENST00000397640Q86WV5
ENSG00000257949ENST00000586891K7EIL0
ENSG00000257949ENST00000588202K7EL09
ENSG00000257949ENST00000590676K7EJS2

Expression (GTEx)

0
10
20
30
40
50
60
70

References

Pubmed IDYearTitleCitations
384188842024CST-polymerase α-primase solves a second telomere end-replication problem.4
384188842024CST-polymerase α-primase solves a second telomere end-replication problem.4
351346162022Pan-cancer analysis reveals that CTC1-STN1-TEN1 (CST) complex may have a key position in oncology.6
358308812022Structures of the human CST-Polα-primase complex bound to telomere templates.34
358315082022Reconstitution of a telomeric replicon organized by CST.20
351346162022Pan-cancer analysis reveals that CTC1-STN1-TEN1 (CST) complex may have a key position in oncology.6
358308812022Structures of the human CST-Polα-primase complex bound to telomere templates.34
358315082022Reconstitution of a telomeric replicon organized by CST.20
332103172021Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA.26
337807182021CST in maintaining genome stability: Beyond telomeres.13
332103172021Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA.26
337807182021CST in maintaining genome stability: Beyond telomeres.13
326279422020An Indian child with Coats plus syndrome due to mutations in STN1.9
326279422020An Indian child with Coats plus syndrome due to mutations in STN1.9
309768122019Mammalian CST averts replication failure by preventing G-quadruplex accumulation.45

Citation

Dessen P

TEN1 (TEN1 subunit of CST complex)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57843/ten1-(ten1-subunit-of-cst-complex)