LAD1 (ladinin 1)

2019-04-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
LadA
FUSION GENES

Other Information

Locus ID:

NCBI: 3898
MIM: 602314
HGNC: 6472
Ensembl: ENSG00000159166

Variants:

dbSNP: 3898
ClinVar: 3898
TCGA: ENSG00000159166
COSMIC: LAD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159166ENST00000367313E9PDI4
ENSG00000159166ENST00000391967O00515
ENSG00000159166ENST00000631576A0A0J9YYF6
ENSG00000159166ENST00000632743A0A0J9YW63
ENSG00000159166ENST00000633953A0A0J9YVY2

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367707732023The Tumorigenic Effect of the High Expression of Ladinin-1 in Lung Adenocarcinoma and Its Potential as a Therapeutic Target.1
367707732023The Tumorigenic Effect of the High Expression of Ladinin-1 in Lung Adenocarcinoma and Its Potential as a Therapeutic Target.1
366138822022Ladinin 1 Shortens Survival via Promoting Proliferation and Enhancing Invasiveness in Lung Adenocarcinoma.0
366138822022Ladinin 1 Shortens Survival via Promoting Proliferation and Enhancing Invasiveness in Lung Adenocarcinoma.0
345163172021High expression of ladinin-1 (LAD1) predicts adverse outcomes: a new candidate docetaxel resistance gene for prostatic cancer (PCa).4
345163172021High expression of ladinin-1 (LAD1) predicts adverse outcomes: a new candidate docetaxel resistance gene for prostatic cancer (PCa).4
293827832018SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.26
293827832018SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors.26
274607032016Basement membrane protein ladinin-1 and the MIF-CD44-β1 integrin signaling axis are implicated in laryngeal cancer metastasis.12
274607032016Basement membrane protein ladinin-1 and the MIF-CD44-β1 integrin signaling axis are implicated in laryngeal cancer metastasis.12
256057892015Long-Term Balancing Selection in LAD1 Maintains a Missense Trans-Species Polymorphism in Humans, Chimpanzees, and Bonobos.45
256057892015Long-Term Balancing Selection in LAD1 Maintains a Missense Trans-Species Polymorphism in Humans, Chimpanzees, and Bonobos.45
208303102010Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.9
208303102010Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.9

Citation

Dessen P

LAD1 (ladinin 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57853/lad1-(ladinin-1)