Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7135
MIM: 191042
HGNC: 11945
Ensembl: ENSG00000159173
Variants:
dbSNP: 7135
ClinVar: 7135
TCGA: ENSG00000159173
COSMIC: TNNI1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Muscle contraction | REACTOME | R-HSA-397014 |
| Striated Muscle Contraction | REACTOME | R-HSA-390522 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38569017 | 2024 | Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease. | 0 |
| 38569017 | 2024 | Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease. | 0 |
| 33158499 | 2021 | Postoperative troponin increases after noncardiac surgery are associated with raised neurofilament light: a prospective observational cohort study. | 7 |
| 33683712 | 2021 | Elevation of fast but not slow troponin I in the circulation of patients with Becker and Duchenne muscular dystrophy. | 9 |
| 33158499 | 2021 | Postoperative troponin increases after noncardiac surgery are associated with raised neurofilament light: a prospective observational cohort study. | 7 |
| 33683712 | 2021 | Elevation of fast but not slow troponin I in the circulation of patients with Becker and Duchenne muscular dystrophy. | 9 |
| 32539541 | 2020 | Cardiac Troponin I Is an Independent Predictor for Mortality in Hospitalized Patients With COVID-19. | 43 |
| 32539541 | 2020 | Cardiac Troponin I Is an Independent Predictor for Mortality in Hospitalized Patients With COVID-19. | 43 |
| 30453890 | 2018 | Troponin I at admission in the intensive care unit predicts the need of dialysis in septic patients. | 0 |
| 30453890 | 2018 | Troponin I at admission in the intensive care unit predicts the need of dialysis in septic patients. | 0 |
| 28585121 | 2017 | Ultra-sensitive troponin I is an independent predictor of incident coronary heart disease in the general population. | 6 |
| 28718245 | 2017 | Left Ventricular Systolic Dysfunction Predicted By Early Troponin I Release After Anthracycline Based Chemotherapy In Breast Cancer Patients. | 6 |
| 28585121 | 2017 | Ultra-sensitive troponin I is an independent predictor of incident coronary heart disease in the general population. | 6 |
| 28718245 | 2017 | Left Ventricular Systolic Dysfunction Predicted By Early Troponin I Release After Anthracycline Based Chemotherapy In Breast Cancer Patients. | 6 |
| 26972631 | 2016 | Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study. | 28 |
Citation
Dessen P
TNNI1 (troponin I1, slow skeletal type)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57856/tumors-explorer/teaching-explorer/
