Identity
HGNC
LOCATION
1q25.3
LOCUSID
ALIAS
C1orf16,EST1C,SGA56M
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9887
MIM: 610964
HGNC: 16792
Ensembl: ENSG00000116698
Variants:
dbSNP: 9887
ClinVar: 9887
TCGA: ENSG00000116698
COSMIC: SMG7
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35511739 | 2022 | SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death. | 1 |
| 35511739 | 2022 | SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death. | 1 |
| 33820915 | 2021 | Critical role of SMG7 in activation of the ATR-CHK1 axis in response to genotoxic stress. | 1 |
| 34172724 | 2021 | SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity. | 33 |
| 33820915 | 2021 | Critical role of SMG7 in activation of the ATR-CHK1 axis in response to genotoxic stress. | 1 |
| 34172724 | 2021 | SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity. | 33 |
| 32602581 | 2020 | Nonsense-mediated decay factor SMG7 sensitizes cells to TNFα-induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1. | 7 |
| 32602581 | 2020 | Nonsense-mediated decay factor SMG7 sensitizes cells to TNFα-induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1. | 7 |
| 31511540 | 2019 | Characterization of SMG7 14-3-3-like domain reveals phosphoserine binding-independent regulation of p53 and UPF1. | 5 |
| 31511540 | 2019 | Characterization of SMG7 14-3-3-like domain reveals phosphoserine binding-independent regulation of p53 and UPF1. | 5 |
| 27771886 | 2017 | Frameshift Mutations of SMG7 Essential for Nonsense-Mediated mRNA Decay in Gastric and Colorectal Cancers. | 2 |
| 27864472 | 2017 | Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways. | 104 |
| 28461625 | 2017 | Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates. | 20 |
| 27771886 | 2017 | Frameshift Mutations of SMG7 Essential for Nonsense-Mediated mRNA Decay in Gastric and Colorectal Cancers. | 2 |
| 27864472 | 2017 | Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways. | 104 |
Citation
Dessen P
SMG7 (SMG7 nonsense mediated mRNA decay factor)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57857/smg7-(smg7-nonsense-mediated-mrna-decay-factor)
