TFCP2L1 (transcription factor CP2 like 1)

2019-04-01  

Identity

HGNC
TFCP2L1
LOCATION
2q14.2
LOCUSID
29842
ALIAS
CRTR1,LBP-9,LBP9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29842
MIM: 609785
HGNC: 17925
Ensembl: ENSG00000115112

Variants:

dbSNP: 29842
ClinVar: 29842
TCGA: ENSG00000115112
COSMIC: TFCP2L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115112ENST00000263707Q9NZI6

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372369262023SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.8
372369262023SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.8
345819372022The Transcription Factor TFCP2L1 is Associated with Myelination via miR708-5p Regulation in the Peripheral Nerve System.0
345819372022The Transcription Factor TFCP2L1 is Associated with Myelination via miR708-5p Regulation in the Peripheral Nerve System.0
343991632021Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development.5
345554102021The transcription factor Tfcp2l1 promotes primordial germ cell-like cell specification of pluripotent stem cells.8
343991632021Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development.5
345554102021The transcription factor Tfcp2l1 promotes primordial germ cell-like cell specification of pluripotent stem cells.8
317097552020Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis.36
317097552020Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis.36
307828422019The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells.19
307828422019The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells.19
293237202018Tfcp2l1 safeguards the maintenance of human embryonic stem cell self-renewal.12
294102482018TFCP2/TFCP2L1/UBP1 transcription factors in cancer.41
293237202018Tfcp2l1 safeguards the maintenance of human embryonic stem cell self-renewal.12

Citation

Dessen P

TFCP2L1 (transcription factor CP2 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57862/tfcp2l1-(transcription-factor-cp2-like-1)