FBXO17 (F-box protein 17)

2019-04-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
FBG4,FBX26,FBXO26,Fbx17

Other Information

Locus ID:

NCBI: 115290
MIM: 609094
HGNC: 18754
Ensembl: ENSG00000269190

Variants:

dbSNP: 115290
ClinVar: 115290
TCGA: ENSG00000269190
COSMIC: FBXO17

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000269190ENST00000292852Q96EF6
ENSG00000269190ENST00000595329Q96EF6
ENSG00000269190ENST00000596025M0QYV7
ENSG00000269190ENST00000599598M0QZ95
ENSG00000269190ENST00000601394M0QYI3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

References

Pubmed IDYearTitleCitations
350444552022F-box protein 17 promotes glioma progression by regulating glycolysis pathway.2
353570592022Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR-217.3
360353752022FBXO17 Inhibits the Wnt/β-Catenin Pathway and Proliferation of Ishikawa Cells.1
350444552022F-box protein 17 promotes glioma progression by regulating glycolysis pathway.2
353570592022Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR-217.3
360353752022FBXO17 Inhibits the Wnt/β-Catenin Pathway and Proliferation of Ishikawa Cells.1
347022782021Identification and validation of an immune-associated RNA-binding proteins signature to predict clinical outcomes and therapeutic responses in colon cancer patients.6
347022782021Identification and validation of an immune-associated RNA-binding proteins signature to predict clinical outcomes and therapeutic responses in colon cancer patients.6
316465572019FBXO17 promotes malignant progression of hepatocellular carcinoma by activating wnt/β-catenin pathway.12
316465572019FBXO17 promotes malignant progression of hepatocellular carcinoma by activating wnt/β-catenin pathway.12
300644932018Clinical significance of FBXO17 gene expression in high-grade glioma.8
303592712018FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells.17
300644932018Clinical significance of FBXO17 gene expression in high-grade glioma.8
303592712018FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells.17
279565282017A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation.19

Citation

Dessen P

FBXO17 (F-box protein 17)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57870/fbxo17-(f-box-protein-17)