ADGRG6 (adhesion G protein-coupled receptor G6)

2019-04-01  

Identity

HGNC
LOCATION
6q24.2
LOCUSID
ALIAS
APG1,DREG,GPR126,LCCS9,PR126,PS1TP2,VIGR
FUSION GENES

Other Information

Locus ID:

NCBI: 57211
MIM: 612243
HGNC: 13841
Ensembl: ENSG00000112414

Variants:

dbSNP: 57211
ClinVar: 57211
TCGA: ENSG00000112414
COSMIC: ADGRG6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112414ENST00000230173Q86SQ4
ENSG00000112414ENST00000296932Q86SQ4
ENSG00000112414ENST00000367608Q86SQ4
ENSG00000112414ENST00000367609Q86SQ4
ENSG00000112414ENST00000435011F5H054
ENSG00000112414ENST00000508295H0YGP2
ENSG00000112414ENST00000540208H0YFM8
ENSG00000112414ENST00000541199F5H2L1

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371542972023Noncoding SNP at rs1663689 represses ADGRG6 via interchromosomal interaction and reduces lung cancer progression.2
372708062023Analysis of GPR126 polymorphisms and their relationship with scoliosis in Marfan syndrome and Marfan-like syndrome in Mexican patients.1
375660662023Adhesion GPCR Gpr126 (Adgrg6) Expression Profiling in Zebrafish, Mouse, and Human Kidney.1
377343712023The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells.1
371542972023Noncoding SNP at rs1663689 represses ADGRG6 via interchromosomal interaction and reduces lung cancer progression.2
372708062023Analysis of GPR126 polymorphisms and their relationship with scoliosis in Marfan syndrome and Marfan-like syndrome in Mexican patients.1
375660662023Adhesion GPCR Gpr126 (Adgrg6) Expression Profiling in Zebrafish, Mouse, and Human Kidney.1
377343712023The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells.1
353948642022Progesterone activates GPR126 to promote breast cancer development via the Gi pathway.9
353948642022Progesterone activates GPR126 to promote breast cancer development via the Gi pathway.9
331797412021Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome.8
332486912021A synthetic method to assay adhesion-family G-protein coupled receptors. Determination of the G-protein coupling profile of ADGRG6(GPR126).7
336294642021GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression.11
341658092021Functional genomics of GPR126 in airway smooth muscle and bronchial epithelial cells.5
331797412021Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome.8

Citation

Dessen P

ADGRG6 (adhesion G protein-coupled receptor G6)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57875/adgrg6-(adhesion-g-protein-coupled-receptor-g6)