Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79991
MIM: 613128
HGNC: 26200
Ensembl: ENSG00000107960
Variants:
dbSNP: 79991
ClinVar: 79991
TCGA: ENSG00000107960
COSMIC: STN1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107960 | ENST00000224950 | Q9H668 |
| ENSG00000107960 | ENST00000369764 | Q9H668 |
Expression (GTEx)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 31327267 | |
| PA448499 | atenolol | Chemical | ClinicalAnnotation | associated | PD | 31327267 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38418884 | 2024 | CST-polymerase α-primase solves a second telomere end-replication problem. | 4 |
| 38418884 | 2024 | CST-polymerase α-primase solves a second telomere end-replication problem. | 4 |
| 38036565 | 2023 | CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection. | 1 |
| 38036565 | 2023 | CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection. | 1 |
| 35134616 | 2022 | Pan-cancer analysis reveals that CTC1-STN1-TEN1 (CST) complex may have a key position in oncology. | 6 |
| 35830881 | 2022 | Structures of the human CST-Polα-primase complex bound to telomere templates. | 34 |
| 35831508 | 2022 | Reconstitution of a telomeric replicon organized by CST. | 20 |
| 35134616 | 2022 | Pan-cancer analysis reveals that CTC1-STN1-TEN1 (CST) complex may have a key position in oncology. | 6 |
| 35830881 | 2022 | Structures of the human CST-Polα-primase complex bound to telomere templates. | 34 |
| 35831508 | 2022 | Reconstitution of a telomeric replicon organized by CST. | 20 |
| 33210317 | 2021 | Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA. | 26 |
| 33780718 | 2021 | CST in maintaining genome stability: Beyond telomeres. | 13 |
| 33941849 | 2021 | Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population. | 5 |
| 34110109 | 2021 | Novel compound heterozygous STN1 variants are associated with Coats Plus syndrome. | 2 |
| 33210317 | 2021 | Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA. | 26 |
Citation
Dessen P
STN1 (STN1 subunit of CST complex)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57880
