TRIP4 (thyroid hormone receptor interactor 4)

2019-04-01  

Identity

HGNC
LOCATION
15q22.31
LOCUSID
ALIAS
ASC-1,ASC1,HsT17391,MDCDC,SMABF1,ZC2HC5
FUSION GENES

Other Information

Locus ID:

NCBI: 9325
MIM: 604501
HGNC: 12310
Ensembl: ENSG00000103671

Variants:

dbSNP: 9325
ClinVar: 9325
TCGA: ENSG00000103671
COSMIC: TRIP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103671ENST00000261884Q15650
ENSG00000103671ENST00000558162H0YKD9
ENSG00000103671ENST00000558820H0YK63
ENSG00000103671ENST00000560475H3BMU9
ENSG00000103671ENST00000560567H0YL91
ENSG00000103671ENST00000560920H0YLN7

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385828622024Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter.0
385828622024Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter.0
377187802023LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis.0
377187802023LINC00668 promoted non-small lung cancer progression by miR-518c-3p/TRIP4 axis.0
352764122022ASC1 complex related conditions: Two novel paediatric patients with TRIP4 pathogenic variants and review of literature.1
352764122022ASC1 complex related conditions: Two novel paediatric patients with TRIP4 pathogenic variants and review of literature.1
342049192021Inherited Defects of the ASC-1 Complex in Congenital Neuromuscular Diseases.3
342049192021Inherited Defects of the ASC-1 Complex in Congenital Neuromuscular Diseases.3
317940732020ASC-1 Is a Cell Cycle Regulator Associated with Severe and Mild Forms of Myopathy.8
322985982020MicroRNA-518-3p suppresses cell proliferation, invasiveness, and migration in colorectal cancer via targeting TRIP4.4
317940732020ASC-1 Is a Cell Cycle Regulator Associated with Severe and Mild Forms of Myopathy.8
322985982020MicroRNA-518-3p suppresses cell proliferation, invasiveness, and migration in colorectal cancer via targeting TRIP4.4
309058202019TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.47
309058202019TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.47
288996852018The Tumor-Promoting Role of TRIP4 in Melanoma Progression and its Involvement in Response to BRAF-Targeted Therapy.3

Citation

Dessen P

TRIP4 (thyroid hormone receptor interactor 4)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57883/trip4-(thyroid-hormone-receptor-interactor-4)