Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54936
MIM: 610624
HGNC: 21304
Ensembl: ENSG00000116863
Variants:
dbSNP: 54936
ClinVar: 54936
TCGA: ENSG00000116863
COSMIC: ADPRS
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116863 | ENST00000373178 | Q9NX46 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38365196 | 2024 | Delineation of ADPRHL2 Variants: Report of Two New Patients with Review of the Literature. | 0 |
| 38365196 | 2024 | Delineation of ADPRHL2 Variants: Report of Two New Patients with Review of the Literature. | 0 |
| 33894202 | 2021 | Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 reveals the basis of metal selectivity and different roles for the two magnesium ions. | 1 |
| 34019811 | 2021 | Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. | 44 |
| 34625544 | 2021 | The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome. | 39 |
| 33894202 | 2021 | Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 reveals the basis of metal selectivity and different roles for the two magnesium ions. | 1 |
| 34019811 | 2021 | Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. | 44 |
| 34625544 | 2021 | The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome. | 39 |
| 32636369 | 2020 | Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair. | 17 |
| 32753484 | 2020 | AI26 inhibits the ADP-ribosylhydrolase ARH3 and suppresses DNA damage repair. | 6 |
| 32636369 | 2020 | Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair. | 17 |
| 32753484 | 2020 | AI26 inhibits the ADP-ribosylhydrolase ARH3 and suppresses DNA damage repair. | 6 |
| 30830864 | 2019 | PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells. | 25 |
| 30830864 | 2019 | PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells. | 25 |
| 29480802 | 2018 | Serine is the major residue for ADP-ribosylation upon DNA damage. | 128 |
Citation
Dessen P
ADPRS (ADP-ribosylserine hydrolase)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57887/adprs-(adp-ribosylserine-hydrolase)
