Identity
HGNC
LOCATION
14q32.12
LOCUSID
ALIAS
C14orf130,LICAS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55148
MIM: 613816
HGNC: 20344
Ensembl: ENSG00000012963
Variants:
dbSNP: 55148
ClinVar: 55148
TCGA: ENSG00000012963
COSMIC: UBR7
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33340455 | 2021 | UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism. | 5 |
| 33571115 | 2021 | NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia. | 9 |
| 34786730 | 2021 | UBR7 acts as a histone chaperone for post-nucleosomal histone H3. | 9 |
| 33340455 | 2021 | UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism. | 5 |
| 33571115 | 2021 | NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia. | 9 |
| 34786730 | 2021 | UBR7 acts as a histone chaperone for post-nucleosomal histone H3. | 9 |
| 30923315 | 2019 | Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor. | 24 |
| 30923315 | 2019 | Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor. | 24 |
| 24664117 | 2014 | Identification and characterization of RING-finger ubiquitin ligase UBR7 in mammalian spermatozoa. | 10 |
| 24664117 | 2014 | Identification and characterization of RING-finger ubiquitin ligase UBR7 in mammalian spermatozoa. | 10 |
Citation
Dessen P
UBR7 (ubiquitin protein ligase E3 component n-recognin 7)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57889/ubr7-(ubiquitin-protein-ligase-e3-component-n-recognin-7)
