RER1 (retention in endoplasmic reticulum sorting receptor 1)

2019-04-01  

Identity

HGNC
LOCATION
1p36.32
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 11079
HGNC: 30309
Ensembl: ENSG00000157916

Variants:

dbSNP: 11079
ClinVar: 11079
TCGA: ENSG00000157916
COSMIC: RER1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157916ENST00000306256A0A0A0MR06
ENSG00000157916ENST00000378512Q5T091
ENSG00000157916ENST00000378513Q5T093
ENSG00000157916ENST00000378518Q5T093
ENSG00000157916ENST00000443438Q5T092
ENSG00000157916ENST00000488353O15258
ENSG00000157916ENST00000488353Q5T094
ENSG00000157916ENST00000605895O15258
ENSG00000157916ENST00000605895Q5T094

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
306305372019RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment.25
306305372019RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment.25
302609512018Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development.8
302609512018Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development.8
288772622017The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome.12
288772622017The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome.12
250963272014Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking.14
253850462014Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease.21
250963272014Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking.14
253850462014Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease.21
234797432013Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels.18
234797432013Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels.18
230430972012Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP).17
231297662012The ubiquitin ligase synoviolin up-regulates amyloid β production by targeting a negative regulator of γ-secretase, Rer1, for degradation.8
230430972012Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP).17

Citation

Dessen P

RER1 (retention in endoplasmic reticulum sorting receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57895/rer1-(retention-in-endoplasmic-reticulum-sorting-receptor-1)