UAP1L1 (UDP-N-acetylglucosamine pyrophosphorylase 1 like 1)

2019-04-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 91373
HGNC: 28082
Ensembl: ENSG00000197355

Variants:

dbSNP: 91373
ClinVar: 91373
TCGA: ENSG00000197355
COSMIC: UAP1L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197355ENST00000360271Q3KQV9
ENSG00000197355ENST00000409858Q3KQV9
ENSG00000197355ENST00000476184A0A087X226

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Amino sugar and nucleotide sugar metabolismKEGGko00520
Amino sugar and nucleotide sugar metabolismKEGGhsa00520
Metabolic pathwaysKEGGhsa01100
Nucleotide sugar biosynthesis, eukaryotesKEGGhsa_M00361
Nucleotide sugar biosynthesis, eukaryotesKEGGM00361

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
334343002021Silencing of UAP1L1 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma.2
334343002021Silencing of UAP1L1 inhibits proliferation and induces apoptosis in esophageal squamous cell carcinoma.2
323108232020Identification of UAP1L1 as tumor promotor in gastric cancer through regulation of CDK6.4
323108232020Identification of UAP1L1 as tumor promotor in gastric cancer through regulation of CDK6.4
300976062019Identification of UAP1L1 as a critical factor for protein O-GlcNAcylation and cell proliferation in human hepatoma cells.19
300976062019Identification of UAP1L1 as a critical factor for protein O-GlcNAcylation and cell proliferation in human hepatoma cells.19

Citation

Dessen P

UAP1L1 (UDP-N-acetylglucosamine pyrophosphorylase 1 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57914/uap1l1-(udp-n-acetylglucosamine-pyrophosphorylase-1-like-1)