FRMD8 (FERM domain containing 8)

2019-04-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
FKSG44,iTAP
FUSION GENES

Other Information

Locus ID:

NCBI: 83786
MIM: 618337
HGNC: 25462
Ensembl: ENSG00000126391

Variants:

dbSNP: 83786
ClinVar: 83786
TCGA: ENSG00000126391
COSMIC: FRMD8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126391ENST00000317568Q9BZ67
ENSG00000126391ENST00000355991Q9BZ67
ENSG00000126391ENST00000416776Q9BZ67
ENSG00000126391ENST00000525156E9PRA3
ENSG00000126391ENST00000526201E9PRP1
ENSG00000126391ENST00000531296Q8N4M4
ENSG00000126391ENST00000533782E9PS62

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375270402023FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.1
375270402023FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.1
298973332018iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.32
298973362018FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.35
298973332018iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.32
298973362018FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.35

Citation

Dessen P

FRMD8 (FERM domain containing 8)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57929/frmd8-(ferm-domain-containing-8)