Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10479
MIM: 300231
HGNC: 11079
Ensembl: ENSG00000198689
Variants:
dbSNP: 10479
ClinVar: 10479
TCGA: ENSG00000198689
COSMIC: SLC9A6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA27745 | ELF2 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38945311 | 2024 | Genes for endosomal pH regulators NHE6 and NHE9 are dysregulated in the substantia nigra in Parkinson's disease. | 0 |
| 38945311 | 2024 | Genes for endosomal pH regulators NHE6 and NHE9 are dysregulated in the substantia nigra in Parkinson's disease. | 0 |
| 37381736 | 2023 | Functional analysis of two SLC9A6 frameshift variants in lymphoblastoid cells from patients with Christianson syndrome. | 2 |
| 37747131 | 2023 | Targeting NHE6 gene expression identifies lysosome and neurodevelopmental mechanisms in a haploid in vitro cell model. | 0 |
| 37794328 | 2023 | Structural and functional implications of SLC13A3 and SLC9A6 mutations: an in silico approach to understanding intellectual disability. | 1 |
| 37381736 | 2023 | Functional analysis of two SLC9A6 frameshift variants in lymphoblastoid cells from patients with Christianson syndrome. | 2 |
| 37747131 | 2023 | Targeting NHE6 gene expression identifies lysosome and neurodevelopmental mechanisms in a haploid in vitro cell model. | 0 |
| 37794328 | 2023 | Structural and functional implications of SLC13A3 and SLC9A6 mutations: an in silico approach to understanding intellectual disability. | 1 |
| 33372133 | 2021 | SCAMP5 plays a critical role in axonal trafficking and synaptic localization of NHE6 to adjust quantal size at glutamatergic synapses. | 8 |
| 33372133 | 2021 | SCAMP5 plays a critical role in axonal trafficking and synaptic localization of NHE6 to adjust quantal size at glutamatergic synapses. | 8 |
| 32277048 | 2020 | Assorted dysfunctions of endosomal alkali cation/proton exchanger SLC9A6 variants linked to Christianson syndrome. | 9 |
| 32277048 | 2020 | Assorted dysfunctions of endosomal alkali cation/proton exchanger SLC9A6 variants linked to Christianson syndrome. | 9 |
| 28635961 | 2017 | Hypoxia-induced mobilization of NHE6 to the plasma membrane triggers endosome hyperacidification and chemoresistance. | 24 |
| 28635961 | 2017 | Hypoxia-induced mobilization of NHE6 to the plasma membrane triggers endosome hyperacidification and chemoresistance. | 24 |
| 27142213 | 2016 | The expanding phenotypic spectrum of female SLC9A6 mutation carriers: a case series and review of the literature. | 21 |
Citation
Dessen P
SLC9A6 (solute carrier family 9 member A6)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57930/slc9a6-(solute-carrier-family-9-member-a6)
