Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9248
MIM: 300207
HGNC: 4506
Ensembl: ENSG00000102195
Variants:
dbSNP: 9248
ClinVar: 9248
TCGA: ENSG00000102195
COSMIC: GPR50
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000102195 | ENST00000218316 | Q13585 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuroactive ligand-receptor interaction | KEGG | ko04080 |
| Neuroactive ligand-receptor interaction | KEGG | hsa04080 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31900622 | 2020 | GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors. | 5 |
| 31900622 | 2020 | GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors. | 5 |
| 31173244 | 2019 | Significant association between GPR50 hypomethylation and AD in males. | 4 |
| 31173244 | 2019 | Significant association between GPR50 hypomethylation and AD in males. | 4 |
| 29572483 | 2018 | The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development. | 15 |
| 29572483 | 2018 | The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development. | 15 |
| 27181993 | 2016 | A pre-eclampsia-associated Epstein-Barr virus antibody cross-reacts with placental GPR50. | 4 |
| 27181993 | 2016 | A pre-eclampsia-associated Epstein-Barr virus antibody cross-reacts with placental GPR50. | 4 |
| 25730005 | 2015 | Uneven evolutionary rate of the melatonin-related receptor gene (GPR50) in primates. | 1 |
| 25798330 | 2015 | Involvement of GPR50 polymorphisms in depression: independent replication in a prospective elderly cohort. | 8 |
| 25730005 | 2015 | Uneven evolutionary rate of the melatonin-related receptor gene (GPR50) in primates. | 1 |
| 25798330 | 2015 | Involvement of GPR50 polymorphisms in depression: independent replication in a prospective elderly cohort. | 8 |
| 21565467 | 2012 | Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern. | 10 |
| 21565467 | 2012 | Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern. | 10 |
| 20351714 | 2011 | Poor replication of candidate genes for major depressive disorder using genome-wide association data. | 119 |
Citation
Dessen P
GPR50 (G protein-coupled receptor 50)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57933/gpr50-(g-protein-coupled-receptor-50)
