CHST5 (carbohydrate sulfotransferase 5)

2019-04-01  

Identity

HGNC
LOCATION
16q23.1
LOCUSID
ALIAS
I-GlcNAc-6-ST,I-GlcNAc6ST,glcNAc6ST-3,gn6st-3,hIGn6ST
FUSION GENES

Other Information

Locus ID:

NCBI: 23563
MIM: 604817
HGNC: 1973
Ensembl: ENSG00000135702

Variants:

dbSNP: 23563
ClinVar: 23563
TCGA: ENSG00000135702
COSMIC: CHST5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135702ENST00000336257Q9GZS9
ENSG00000135702ENST00000565039H3BMG8

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Keratan sulfate/keratin metabolismREACTOMER-HSA-1638074
Keratan sulfate biosynthesisREACTOMER-HSA-2022854

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
300934102018Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis.12
300934102018Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis.12
198442552010Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.10
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.26
198442552010Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.10
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.26
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
176901042007Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans.25
176901042007Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans.25

Citation

Dessen P

CHST5 (carbohydrate sulfotransferase 5)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57937/submit-meetings/